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Oit3tm1Zgh
Targeted Allele Detail
Nomenclature
Symbol: Oit3tm1Zgh
Name: oncoprotein induced transcript 3; targeted mutation 1, Ze-Guang Han
MGI ID: MGI:5315854
Gene: Oit3  Location: Chr10:59422960-59441779 bp, - strand  Genetic Position: Chr10, 29.54 cM, cytoband B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181913
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 1 and 2. Western blot analysis confirmed the absence of protein expression in the liver and kidney, (J:181913)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oit3 Mutation:  29 strains or lines available
References
Original:  J:181913 Yan B, et al., OIT3 deficiency impairs uric acid reabsorption in renal tubule. FEBS Lett. 2012 Mar 23;586(6):760-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory