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Tg(GAL4-PABPN1*A16)#Cath
Transgene Detail
Summary
Symbol: Tg(GAL4-PABPN1*A16)#Cath
Name: transgene insertion, Charles A Thornton
MGI ID: MGI:5314745
Synonyms: GAL4-tk-PABmut
Transgene: Tg(GAL4-PABPN1*A16)#Cath  Location: unknown  
Alliance: Tg(GAL4-PABPN1*A16)#Cath page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(GAL4-PABPN1*A16)#Cath expresses 1 gene
 
Mutation detailsThis transgene consists of a human PABPN1 minigene with an insertion of an additional six alanine codons to the polyalanine tract (for a total of 16 alanines) under the control of four GAL4 response elements linked to the minimal thymidine kinase promoter. Four lines were made, however the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:178541)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:178541 Mankodi A, et al., Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy. Neurobiol Dis. 2012 Jan;45(1):539-46
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory