Ucma^tm1Msto
Targeted Allele Detail

Summary

• Symbol: Ucma^tm1Msto
• Name: upper zone of growth plate and cartilage matrix associated; targeted mutation 1, Michael Stock
• MGI ID: MGI:5314628
• Gene: Ucma Location: Chr2:4980933-4990559 bp, + strand Genetic Position: Chr2, 3.11 cM
• Alliance: Ucma^tm1Msto page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181901
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ/neo cassette was inserted into exon 1. Western blot analysis confirms the absence of protein expression in epiphyseal cartilage. (J:181901)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ucma Mutation: 6 strains or lines available

References

• Original: J:181901 Eitzinger N, et al., Ucma is not necessary for normal development of the mouse skeleton. Bone. 2012 Mar;50(3):670-80
• All: 2 reference(s)