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Syktm1.1Nns
Targeted Allele Detail
Nomenclature
Symbol: Syktm1.1Nns
Name: spleen tyrosine kinase; targeted mutation 1, Nicholas N Smithers
MGI ID: MGI:5314125
Synonyms: Sykfl
Gene: Syk  Location: Chr13:52583173-52648792 bp, + strand  Genetic Position: Chr13, 27.41 cM, cytoband B-C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181715
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 11 was floxed. Cre-mediated recombination removes the floxed neo cassette. (J:181715)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syk Mutation:  28 strains or lines available
References
Original:  J:181715 Finney BA, et al., CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development. Blood. 2012 Feb 16;119(7):1747-56
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory