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Gt(ROSA)26Sortm3(Runx2)Flng
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm3(Runx2)Flng
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Fanxin Long
MGI ID: MGI:5311032
Synonyms: R26Runx2
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180304
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm3(Runx2)Flng expresses 1 gene
 
Mutation detailsThe insertional construct contained a floxed neo/STOP cassette, the mouse Runx2 cDNA encoding the MASNS isoform, an IRES, EGFP and polyadenylation sequence. (J:180304)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  287 strains or lines available
References
Original:  J:180304 Tu X, et al., Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation. Dev Biol. 2012 Feb 1;362(1):76-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory