About   Help   FAQ
Ctnnb1tm2Kba
Targeted Allele Detail
Summary
Symbol: Ctnnb1tm2Kba
Name: catenin beta 1; targeted mutation 2, Konrad Basler
MGI ID: MGI:5308945
Synonyms: Beta-catenindeltaC
Gene: Ctnnb1  Location: Chr9:120762466-120789573 bp, + strand  Genetic Position: Chr9, 72.19 cM
Alliance: Ctnnb1tm2Kba page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:178971
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Hypomorph, Inserted expressed sequence)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA premature stop codon followed by a frameshift mutation were introduced at amino acid position 673 in exon 13 and this exon was fused to exon 15 via homologous recombination. (J:178971)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctnnb1 Mutation:  49 strains or lines available
References
Original:  J:178971 Valenta T, et al., Probing transcription-specific outputs of beta-catenin in vivo. Genes Dev. 2011 Dec 15;25(24):2631-43
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory