Tmem190^tm1Pmkf
Targeted Allele Detail

Summary

• Symbol: Tmem190^tm1Pmkf
• Name: transmembrane protein 190; targeted mutation 1, Paul Primakoff
• MGI ID: MGI:5308734
• Gene: Tmem190 Location: Chr7:4785936-4787340 bp, + strand Genetic Position: Chr7, 2.77 cM, cytoband A1
• Alliance: Tmem190^tm1Pmkf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180946
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with a neo cassette via homologous recombination. Immunoblot analysis confirmed the absence of protein in male germ cells from homozygous mice. (J:180946)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem190 Mutation: 6 strains or lines available

References

• Original: J:180946 Nishimura H, et al., Characterization of mouse sperm TMEM190, a small transmembrane protein with the trefoil domain: evidence for co-localization with IZUMO1 and complex formation with other sperm proteins. Reproduction. 2011 Apr;141(4):437-51
• All: 1 reference(s)