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Tmem190tm1Pmkf
Targeted Allele Detail
Nomenclature
Symbol: Tmem190tm1Pmkf
Name: transmembrane protein 190; targeted mutation 1, Paul Primakoff
MGI ID: MGI:5308734
Gene: Tmem190  Location: Chr7:4782937-4784341 bp, + strand  Genetic Position: Chr7, 2.77 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180946
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was replaced with a neo cassette via homologous recombination. Immunoblot analysis confirmed the absence of protein in male germ cells from homozygous mice. (J:180946)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem190 Mutation:  3 strains or lines available
References
Original:  J:180946 Nishimura H, et al., Characterization of mouse sperm TMEM190, a small transmembrane protein with the trefoil domain: evidence for co-localization with IZUMO1 and complex formation with other sperm proteins. Reproduction. 2011 Apr;141(4):437-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/20/2017
MGI 6.10
The Jackson Laboratory