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Tg(RP3-340H11)29Kel
Transgene Detail
Nomenclature
Symbol: Tg(RP3-340H11)29Kel
Name: transgene insertion 29, Gavin Derek Kelsey
MGI ID: MGI:5308378
Synonyms: Tg(RP21-340H11)29Kel, TNDM29
Transgene: Tg(RP3-340H11)29Kel  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/Ca)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details
Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
A second transgenic line, designated TNDM35, was estimated to carry 2-5 copies of the PAC, expressed the human transcripts at lower levels than TNDM29 and did not exhibit the early hyperglycemic phenotype. (J:91709)

References
Original:  J:91709 Ma D, et al., Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM. J Clin Invest. 2004 Aug;114(3):339-48
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory