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Gata4tm3.1Wtp
Targeted Allele Detail
Nomenclature
Symbol: Gata4tm3.1Wtp
Name: GATA binding protein 4; transgene insertion 3.1, William T Pu
MGI ID: MGI:5308206
Synonyms: CVDC/B2B program mutation, GATA4flbio
Gene: Gata4  Location: Chr14:63198922-63271692 bp, - strand  Genetic Position: Chr14, 33.24 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:179371
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Project Collection: B2B/CvDC
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsFlag and bio epitope tags and an FRT flanked neo cassette were inserted at the C terminus of the gene via homologous recombination. Flp mediated recombination removed the neo cassette. (J:179371)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gata4 Mutation:  23 strains or lines available
References
Original:  J:179371 He A, et al., PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev. 2012 Jan 1;26(1):37-42
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory