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Slc4a5tm1.1Boet
Targeted Allele Detail
Nomenclature
Symbol: Slc4a5tm1.1Boet
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5; targeted mutation 1, Thomas Boettger
MGI ID: MGI:5306980
Synonyms: Slc4a5delta7
Gene: Slc4a5  Location: Chr6:83219828-83304945 bp, + strand  Genetic Position: Chr6, 35.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180608
Parent Cell Line:  MPI-II (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed the neo cassette. A quantitative mass-spectroscopy-based proteomic approach (SILAC-MS) confirmed the absence of protein expression. (J:180608)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc4a5 Mutation:  24 strains or lines available
References
Original:  J:180608 Groger N, et al., Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis. Hum Mol Genet. 2012 Mar 1;21(5):1025-36
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory