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Col3a1m1Lsmi
Spontaneous Allele Detail
Nomenclature
Symbol: Col3a1m1Lsmi
Name: collagen, type III, alpha 1; mutation 1, Lee Smith
MGI ID: MGI:5306912
Synonyms: Col3a1delta
Gene: Col3a1  Location: Chr1:45311538-45349706 bp, + strand  Genetic Position: Chr1, 23.67 cM
Mutation
origin
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intergenic deletion
    The 185 kb deletion encompasses the first 38 exons. (J:180733)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col3a1 Mutation:  4 strains or lines available
Notes
Isolated from ES cells targeted to produce Mrotm1H.
References
Original:  J:180733 Smith LB, et al., Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers-Danlos syndrome. Cardiovasc Res. 2011 Apr 1;90(1):182-90
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory