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Ephb1tm1.1Henk
Targeted Allele Detail
Nomenclature
Symbol: Ephb1tm1.1Henk
Name: Eph receptor B1; targeted mutation 1.1, Mark Henkmeyer
MGI ID: MGI:5306414
Synonyms: EphB1T-lacZ
Gene: Ephb1  Location: Chr9:101922128-102354693 bp, - strand  Genetic Position: Chr9, 54.15 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176056
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA lacZ was inserted in frame within exon 9 immediately following codon 578. Cre-mediated recombination removed the floxed neo cassette. (J:176056, J:184158)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ephb1 Mutation:  3 strains or lines available
References
Original:  J:176056 Thakar S, et al., Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping. Nat Commun. 2011;2:431
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory