Csf1^tm1.2Sabw
Targeted Allele Detail

Summary

• Symbol: Csf1^tm1.2Sabw
• Name: colony stimulating factor 1 (macrophage); targeted mutation 1.2, Sherry Abboud Werner
• MGI ID: MGI:5305707
• Gene: Csf1 Location: Chr3:107648364-107667785 bp, - strand
• Alliance: Csf1^tm1.2Sabw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180199
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 through 6 were removed by cre-mediated recombination of Csf1^tm1.1Sabw. ELISA confirmed the absence of protein expression in the serum. (J:180199)

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csf1 Mutation: 45 strains or lines available

References

• Original: J:180199 Harris SE, et al., Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects. Bone. 2012 Jan;50(1):42-53
• All: 3 reference(s)