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Targeted Allele Detail
Symbol: Ccne1tm3.1Pisc
Name: cyclin E1; targeted mutation 3.1, Piotr Sicinski
MGI ID: MGI:5304324
Synonyms: CcnE1f, E1flox
Gene: Ccne1  Location: Chr7:38097984-38107490 bp, - strand  Genetic Position: Chr7, 25.35 cM
Germline Transmission:  Earliest citation of germline transmission: J:178882
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsLoxP sites were inserted into intron 4 and 11. An FRT-flanked hygro cassette inserted into intron 11 was removed by flp-mediated recombination. (J:178882)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccne1 Mutation:  4 strains or lines available
Original:  J:178882 Odajima J, et al., Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18;21(4):655-68
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory