Tg(Scgb1a1-rtTA)2Jaw
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-rtTA)2Jaw
• Name: transgene insertion 2, Jeffrey A Whitsett
• MGI ID: MGI:5301895
• Synonyms: SP-C-rtTA (Line 2)
• Transgene: Tg(Scgb1a1-rtTA)2Jaw Location: unknown
• Alliance: Tg(Scgb1a1-rtTA)2Jaw page

Transgene origin

• Strain of Origin: C57BL/6 and 129

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The transgenic construct contains 3.7kb sequence of the rat Scgb1a1 (secretoglobin, family 1A, member 1 (uteroglobin) gene promoter, the reverse tetracycline regulatable transactivator protein (rtTA) gene, and 2.0kb sequence of the human grouth hormone gene, containing introns and polyadenylation site. Line 2 was generated. (J:179352)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:179352 Perl AK, et al., Conditional expression of genes in the respiratory epithelium in transgenic mice: cautionary notes and toward building a better mouse trap. Am J Respir Cell Mol Biol. 2009 Jan;40(1):1-3
• All: 15 reference(s)