Skor2Tn(sb-Tyr)1799B.CA7Ove
Transposon induced Allele Detail
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Symbol: |
Skor2Tn(sb-Tyr)1799B.CA7Ove |
Name: |
SKI family transcriptional corepressor 2; transposon insertion 1799B.CA7, Paul A Overbeek |
MGI ID: |
MGI:5300464 |
Gene: |
Skor2 Location: Chr18:76944100-76988037 bp, + strand Genetic Position: Chr18, 51.93 cM
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Alliance: |
Skor2Tn(sb-Tyr)1799B.CA7Ove page
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Allele Type: |
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Transposon induced (Reporter) |
Mutation: |
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Transposon insertion
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Mutation details: Mobilization of transposon from TgTn(sb-Tyr)1799BOve transgenic mice with Sleeping Beauty transposase from Tg(CAG-sb10)1Dla transgenic mice results in the integration of the transposon in a non-coding region 237 kbp upstream from the start codon of Skor2 [NCB137/mm9; 76,860,053] through intron 8 of Skor2 [NCB137/mm9; 77,133,014] deleting exons 1 through 8. Real-time RT-PCR confirmed the absence of transcript expression in the P0 cerebellum.
(J:178818)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Skor2 Mutation: |
45 strains or lines available
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Original: |
J:178818 Wang B, et al., Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct;138(20):4487-97 |
All: |
1 reference(s) |
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