About   Help   FAQ
Sox10M2J
Spontaneous Allele Detail
Nomenclature
Symbol: Sox10M2J
Name: SRY (sex determining region Y)-box 10; mutation 2 Jackson
MGI ID: MGI:5300065
Gene: Sox10  Location: Chr15:79039113-79048690 bp, - strand  Genetic Position: Chr15, 37.7 cM
Mutation
origin
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsA spontaneous T-to-A transition at position 79,163,324 (GRCm38) results in the replacement of asparagine with lysine at residue 131 (p.N131K). (J:181083, J:222308)
Inheritance:    Dominant
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox10 Mutation:  26 strains or lines available
References
Original:  J:181083 Dionne L, et al., Sox10M2J, A Point Mutation Causing White Spotting. MGI Direct Data Submission. 2012;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory