Sox10^M2J
Spontaneous Allele Detail

Summary

• Symbol: Sox10^M2J
• Name: SRY (sex determining region Y)-box 10; mutation 2 Jackson
• MGI ID: MGI:5300065
• Gene: Sox10 Location: Chr15:79039113-79048690 bp, - strand Genetic Position: Chr15, 37.7 cM
• Alliance: Sox10^M2J page

Mutation origin

• Strain of Origin: B6Ei.Cg-Nr0b1^tm1.1Lja Tg(Sry)2Ei Chr Y^AKR/EiJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A spontaneous T-to-A transition at position 79,163,324 (GRCm38) results in the replacement of asparagine with lysine at residue 131 (p.N131K). (J:181083, J:222308)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sox10 Mutation: 33 strains or lines available

References

• Original: J:181083 Dionne L, et al., Sox10^M2J, A Point Mutation Causing White Spotting. MGI Direct Data Submission. 2012
• All: 2 reference(s)