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Tg(SOD1*H46R)#Maw
Transgene Detail
Nomenclature
Symbol: Tg(SOD1*H46R)#Maw
Name: transgene insertion, Manabu Wada
MGI ID: MGI:5297587
Synonyms: H46R SOD1 Tg
Transgene: Tg(SOD1*H46R)#Maw  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(SOD1*H46R)#Maw expresses 1 gene
 
Mutation detailsAn 11.5kb genomic fragment containing the entire human SOD1 gene was mutated so that the histidine residue at position 46 was replaced by arginine. (J:99701)
Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:99701 Chang-Hong R, et al., Neuroprotective effect of oxidized galectin-1 in a transgenic mouse model of amyotrophic lateral sclerosis. Exp Neurol. 2005 Jul;194(1):203-11
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory