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b2b191Clo
Chemically induced Allele Detail
Nomenclature
Symbol: b2b191Clo
Name: Mutant line 191; Bench to Bassinet Program (B2B/CVDC), mutation 191 Cecilia Lo
MGI ID: MGI:5297421
Synonyms: Shizou (SHIN-TSO)
Gene: b2b191Clo  Location: unknown  
EFIC Summary

Show the 15 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: B2B/CvDC
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Undefined
    This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any b2b191Clo Mutation:  0 strains or lines available
Notes
Summative Diagnosis:
Cardiovascular defects: Double outlet right ventricle (DORV),overriding aorta, ventricular septal defects (VSD), atrio-ventricular septal defects (AVSD), pulmonary stenosis (outflow track and main-pulmonary artery), right aortic arch (RAA), and left coronary artery fistula.
Non-cardiovascular defect: Cleft palate

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
0606 DORV + AVSD (AV canal)
1310 Ventricular septal defect, membranous
1320 Ventricular septal defect, muscular
2230 Coronary fistula (arterio-venous or arterio-cameral)
2721 Right aortic arch with abnormal branching pattern
3804 Congenital heart disease

References
Original:  J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-15;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory