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Targeted Allele Detail
Symbol: Epb41l3tm1.1Jglt
Name: erythrocyte membrane protein band 4.1 like 3; targeted mutation 1.1, Jean-Antoine Girault
MGI ID: MGI:5297225
Synonyms: protein 4.1BKO3
Gene: Epb41l3  Location: Chr17:69156810-69289985 bp, + strand  Genetic Position: Chr17, 40.15 cM
Limb clasping and gait abnormalities in Epb41l3tm1.1Jglt/Epb41l3tm1.1Jglt mice

Show the 4 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:177866
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 3. A floxed hygro-GFP cassette was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the hygro-GFP cassette. The absence of protein expression was confirmed by western blot analysis on brain and sciatic nerve extract. (J:177866)
Generation of the Epb41l3tm1.1Jglt allele
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epb41l3 Mutation:  4 strains or lines available
Original:  J:177866 Cifuentes-Diaz C, et al., Protein 4.1B contributes to the organization of peripheral myelinated axons. PLoS One. 2011;6(9):e25043
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.0
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