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Sgcetm1Vinni
Targeted Allele Detail
Summary
Symbol: Sgcetm1Vinni
Name: sarcoglycan, epsilon; targeted mutation 1, Vincenzo Nigro
MGI ID: MGI:5296936
Gene: Sgce  Location: Chr6:4674350-4747180 bp, - strand  Genetic Position: Chr6, 1.81 cM
Alliance: Sgcetm1Vinni page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:177563
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 6 through 9 were replaced with a lacZ and neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:177563)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sgce Mutation:  41 strains or lines available
References
Original:  J:177563 Lancioni A, et al., Combined deficiency of alpha and epsilon sarcoglycan disrupts the cardiac dystrophin complex. Hum Mol Genet. 2011 Dec 1;20(23):4644-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory