Fat3^tm1.1Good
Targeted Allele Detail

Summary

• Symbol: Fat3^tm1.1Good
• Name: FAT atypical cadherin 3; targeted mutation 1.1, Lisa Goodrich
• MGI ID: MGI:5295414
• Synonyms: fat3^floxed
• Gene: Fat3 Location: Chr9:15821485-16412581 bp, - strand Genetic Position: Chr9, 5.16 cM
• Alliance: Fat3^tm1.1Good page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176668
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 23. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 23. Flp-mediated recombination removed the neo cassette and left exon 23 floxed. (J:176668)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fat3 Mutation: 240 strains or lines available

References

• Original: J:176668 Deans MR, et al., Control of neuronal morphology by the atypical cadherin Fat3. Neuron. 2011 Sep 8;71(5):820-32
• All: 4 reference(s)