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Fat3tm1.1Good
Targeted Allele Detail
Nomenclature
Symbol: Fat3tm1.1Good
Name: FAT atypical cadherin 3; targeted mutation 1.1, Lisa Goodrich
MGI ID: MGI:5295414
Synonyms: fat3floxed
Gene: Fat3  Location: Chr9:15821485-16412581 bp, - strand  Genetic Position: Chr9, 5.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176668
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 23. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 23. Flp-mediated recombination removed the neo cassette and left exon 23 floxed. (J:176668)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fat3 Mutation:  135 strains or lines available
References
Original:  J:176668 Deans MR, et al., Control of neuronal morphology by the atypical cadherin Fat3. Neuron. 2011 Sep 8;71(5):820-32
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory