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Transgene Detail
Symbol: Tg(ACTA1-Atp2a1)1Jmol
Name: transgene insertion 1, Jeffery D Molkentin
MGI ID: MGI:5294556
Transgene: Tg(ACTA1-Atp2a1)1Jmol  Location: unknown  
Strain of Origin:  FVB
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(ACTA1-Atp2a1)1Jmol expresses 1 gene
Mutation detailsA transgenic vector was designed to express the rat skeletal muscle isoform of SERCA1 (Atp2a1) cDNA under the regulatory control of a human skeletal alpha actin (ACTA1) promoter. (J:171822)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:171822 Goonasekera SA, et al., Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. J Clin Invest. 2011 Mar 1;121(3):1044-52
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory