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Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak
Transgene Detail
Nomenclature
Symbol: Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak
Name: transgene insertion 1, Haruhiko Akiyama
MGI ID: MGI:5293615
Synonyms: CAG-mRFP1floxed-Sox9-EGFP, CAG-Sox9
Transgene: Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak expresses 1 gene
 
Mutation detailsThe transgene consists of the CAG promoter, a cassette containing a loxP-flanked mRFP1 gene and 4 tandem polyadneylation sites, the human SOX9 cDNA with a 3x hemagglutinin epitope tag, and an IRES-EGFP-polyA sequence. The vector was injected into C57BL/6 oocytes to generated mice. 8 founders were obtained and one line that showed significant levels of (ubiquitous) mRFP1 expression was chosen for further study. (J:176952)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:176952 Kim Y, et al., Generation of transgenic mice for conditional overexpression of Sox9. J Bone Miner Metab. 2011 Jan;29(1):123-9
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/26/2022
MGI 6.21
The Jackson Laboratory