Rtn4r^rgsc1836
Chemically induced Allele Detail

Summary

• Symbol: Rtn4r^rgsc1836
• Name: reticulon 4 receptor; RIKEN Genomic Sciences Center, 1836
• MGI ID: MGI:5293442
• Synonyms: Rtn4r-R189H
• Gene: Rtn4r Location: Chr16:17945506-17970272 bp, + strand Genetic Position: Chr16, 11.23 cM, cytoband B1
• Alliance: Rtn4r^rgsc1836 page

Mutation origin

• Strain of Origin: C57BL/6JJcl
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to A transition that results in the amino acid substitution of histidine for arginine at position 189 (R189H). (J:176996)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn4r Mutation: 24 strains or lines available

References

• Original: J:176996 Lazar NL, et al., Missense mutation of the reticulon-4 receptor alters spatial memory and social interaction in mice. Behav Brain Res. 2011 Oct 10;224(1):73-9
• All: 1 reference(s)