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Gt(ROSA)26Sortm1Lrsn
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm1Lrsn
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Nils-Goran Larsson
MGI ID: MGI:5292496
Synonyms: Gt(ROSA26)SorStop-mito-YFP, ROSA26lox-Stop-lox-mito-YFP, ROSA26SmY
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176022
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Design of lox-Stop-lox-mito-YFP and targeting to the ROSA26 locus to generate the Gt(ROSA)26Sortm1Lrsn and Gt(ROSA)26Sortm1.1Lrsn alleles
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  241 strains or lines available
References
Original:  J:176022 Sterky FH, et al., Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12937-42
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory