About   Help   FAQ
Tctn2tm1.1Reit
Targeted Allele Detail
Nomenclature
Symbol: Tctn2tm1.1Reit
Name: tectonic family member 2; targeted mutation 1.1, Jeremy Reiter
MGI ID: MGI:5292130
Gene: Tctn2  Location: Chr5:124598749-124627738 bp, + strand  Genetic Position: Chr5, 63.68 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173396
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1. A floxed puro cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neo cassette and exons 1 through 3. (J:173396)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tctn2 Mutation:  22 strains or lines available
Notes
The allele was originally generated in ES cells containing Tctn1Gt(KST296)Byg.
References
Original:  J:173396 Sang L, et al., Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13;145(4):513-28
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/14/2020
MGI 6.14
The Jackson Laboratory