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Targeted Allele Detail
Symbol: Cd101tm1.1Dil
Name: CD101 antigen; targeted mutation 1.1, Linda Wicker
MGI ID: MGI:5288503
Gene: Cd101  Location: Chr3:100900845-100936872 bp, - strand  Genetic Position: Chr3, 43.9 cM
Germline Transmission:  Earliest citation of germline transmission: J:175943
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. The absence of protein expression was confirmed by cell sorting on bone marrow and spleen cells. (J:175943)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd101 Mutation:  34 strains or lines available
Original:  J:175943 Rainbow DB, et al., Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice. J Immunol. 2011 Jul 1;187(1):325-36
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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