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Cd101tm1.1Dil
Targeted Allele Detail
Nomenclature
Symbol: Cd101tm1.1Dil
Name: CD101 antigen; targeted mutation 1.1, Linda Wicker
MGI ID: MGI:5288503
Gene: Cd101  Location: Chr3:100993529-101029556 bp, - strand  Genetic Position: Chr3, 43.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175943
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. The absence of protein expression was confirmed by cell sorting on bone marrow and spleen cells. (J:175943)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd101 Mutation:  23 strains or lines available
References
Original:  J:175943 Rainbow DB, et al., Evidence that Cd101 is an autoimmune diabetes gene in nonobese diabetic mice. J Immunol. 2011 Jul 1;187(1):325-36
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory