Tg(Tpbpa-cre,-EGFP)5Jcc
Transgene Detail

Summary

• Symbol: Tg(Tpbpa-cre,-EGFP)5Jcc
• Name: transgene insertion 5, James C Cross
• MGI ID: MGI:5287872
• Synonyms: Tpbpa-Cre, Tpbpa-Cre-GFP
• Transgene: Tg(Tpbpa-cre,-EGFP)5Jcc Location: unknown
• Alliance: Tg(Tpbpa-cre,-EGFP)5Jcc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tpbpa-cre,-EGFP)5Jcc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Tpbpa

• Mutation details: Transgenic mice were generated using a construct in which a cre recombinase-IRES-EGFP cassette was cloned downstream of the Tpbpa promoter. Three independent lines were obtained and all lines produced similar temporal and spatial expression patterns of cre-EGFP that correlated with those of the endogenous Tpbpa gene. Line 5 was used for further studies as it showed earliest onset of expression (around E8.0). Activity of cre recombinase in reporter assays also was detected by E8.0. (J:122534)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tpbpa (species not specified) Summary of all recombinase alleles driven by Tpbpa. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available

References

• Original: J:122534 Simmons DG, et al., Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. Dev Biol. 2007 Apr 15;304(2):567-78
• All: 12 reference(s)