About   Help   FAQ
Dnm3tm1.2Pdc
Targeted Allele Detail
Nomenclature
Symbol: Dnm3tm1.2Pdc
Name: dynamin 3; targeted mutation 1.2, Pietro De Camilli
MGI ID: MGI:5285526
Gene: Dnm3  Location: Chr1:161982453-162478034 bp, - strand  Genetic Position: Chr1, 69.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175247
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/Sv and C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed exon 2 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on brain, testis, and lung extracts. (J:175247)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dnm3 Mutation:  21 strains or lines available
References
Original:  J:175247 Raimondi A, et al., Overlapping role of dynamin isoforms in synaptic vesicle endocytosis. Neuron. 2011 Jun 23;70(6):1100-14
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/18/2017
MGI 6.08
The Jackson Laboratory