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Hilpdatm1.1Nat
Targeted Allele Detail
Summary
Symbol: Hilpdatm1.1Nat
Name: hypoxia inducible lipid droplet associated; targeted mutation 1.1, Jeremy Nathans
MGI ID: MGI:5285399
Gene: Hilpda  Location: Chr6:29272487-29275445 bp, + strand  Genetic Position: Chr6, 12.36 cM
Alliance: Hilpdatm1.1Nat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175369
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted on either side of the single coding exon. The open reading frame for a membrane tethered human placental alkaline phosphatase (hPLAP) was placed after the second loxP site. An FRT-flanked neomycin selectable marker used for ES cell selection (located just downstream of the alkaline phosphatase reporter) was removed by flp-mediated recombination. (J:175369)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hilpda Mutation:  10 strains or lines available
References
Original:  J:175369 Nathans J, Direct Data Submission 2011/09/14. MGI Direct Data Submission. 2011;
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory