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Cd68tm1Shnd
Targeted Allele Detail
Nomenclature
Symbol: Cd68tm1Shnd
Name: CD68 antigen; targeted mutation 1, Christian Schindler
MGI ID: MGI:5285208
Gene: Cd68  Location: Chr11:69664213-69666153 bp, - strand  Genetic Position: Chr11, 42.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175275
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neo cassette was inserted downstream of the transcription initiation site. The absence of protein expression was confirmed by western blot analysis on peritoneal-elicited cell extracts. (J:175275)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd68 Mutation:  19 strains or lines available
References
Original:  J:175275 Song L, et al., Deletion of the murine scavenger receptor CD68. J Lipid Res. 2011 Aug;52(8):1542-50
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory