Wnt7a^tm1.1Tesp
Targeted Allele Detail

Summary

• Symbol: Wnt7a^tm1.1Tesp
• Name: wingless-type MMTV integration site family, member 7A; targeted mutation 1.1, Thomas E Spencer
• MGI ID: MGI:5285199
• Synonyms: Wnt7a^fl
• Gene: Wnt7a Location: Chr6:91340963-91388335 bp, - strand Genetic Position: Chr6, 40.45 cM
• Alliance: Wnt7a^tm1.1Tesp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175291
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Flp-mediated recombination removed the neo cassette and left exon 2 floxed. (J:175291)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt7a Mutation: 25 strains or lines available

References

• Original: J:175291 Dunlap KA, et al., Postnatal deletion of wnt7a inhibits uterine gland morphogenesis and compromises adult fertility in mice. Biol Reprod. 2011 Aug;85(2):386-96
• All: 2 reference(s)