Fads1^{Gt(IST11525H2)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Fads1^{Gt(IST11525H2)Tigm}
• Name: fatty acid desaturase 1; gene trap IST11525H2, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5147023
• Gene: Fads1 Location: Chr19:10160252-10174241 bp, + strand Genetic Position: Chr19, 6.54 cM
• Alliance: Fads1^{Gt(IST11525H2)Tigm} page

Mutation origin

• Mutant Cell Line: IST11525H2
• Germline Transmission: Earliest citation of germline transmission: J:186265
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted into intron 1. RT-qPCR confirmed the absence of protein expression in the colon mucosa and liver. (J:186265)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST11525H2HMR1	JM187884 ; (MGI Seq Detail)	inverse PCR	Chr19:10160880-10161139 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Fads1^{Gt(IST11525H2)Tigm} allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Fads1 Mutation: 29 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)