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Tg(Vav1-ERG)#Jpim
Transgene Detail
Nomenclature
Symbol: Tg(Vav1-ERG)#Jpim
Name: transgene insertion, John E Pimanda
MGI ID: MGI:5141633
Synonyms: ERG Tg, vav-ERG3
Transgene: Tg(Vav1-ERG)#Jpim  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Vav1-ERG)#Jpim expresses 1 gene
 
Mutation detailsA 1.4-kb fragment of the human hematopoietic isoform of ERG (ERG3) is under the control fo the Vav1 promoter. Three founders were established. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:174808)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:174808 Thoms JA, et al., ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer. Blood. 2011 Jun 30;117(26):7079-89
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/21/2021
MGI 6.17
The Jackson Laboratory