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Targeted Allele Detail
Symbol: Neto2tm1Mci
Name: neuropilin (NRP) and tolloid (TLL)-like 2; targeted mutation 1, Roderick R McInnes
MGI ID: MGI:5141222
Gene: Neto2  Location: Chr8:85636588-85700919 bp, - strand  Genetic Position: Chr8, 41.61 cM, cytoband C4
Germline Transmission:  Earliest citation of germline transmission: J:174557
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 3 - 6 were replaced with a neo cassette via homologous recombination. Immunoblot analysis of brain lysates from homozygous mice confirms the absence of protein expression. (J:174557)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Neto2 Mutation:  5 strains or lines available
Original:  J:174557 Tang M, et al., Neto1 Is an Auxiliary Subunit of Native Synaptic Kainate Receptors. J Neurosci. 2011 Jul 6;31(27):10009-10018
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory