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Amer1tm1.2Nbar
Targeted Allele Detail
Nomenclature
Symbol: Amer1tm1.2Nbar
Name: APC membrane recruitment 1; targeted mutation 1.2, Nabeel Bardeesy
MGI ID: MGI:5086004
Gene: Amer1  Location: ChrX:95420318-95444872 bp, - strand  Genetic Position: ChrX, 41.99 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173242
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and second loxP site were inserted in the untranslated region of exon 2 via homologous recombination. Cre mediated recombination removed the coding region of exon 2. (J:173242)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 21 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Amer1 Mutation:  1 strain or line available
References
Original:  J:173242 Moisan A, et al., The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification. Dev Cell. 2011 May 17;20(5):583-96
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory