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Nlrp10tm1Seis
Targeted Allele Detail
Nomenclature
Symbol: Nlrp10tm1Seis
Name: NLR family, pyrin domain containing 10; targeted mutation 1, Stephanie C Eisenbarth
MGI ID: MGI:5085851
Gene: Nlrp10  Location: Chr7:108921853-108930158 bp, - strand  Genetic Position: Chr7, 57.21 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173245
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 including the translation start site were replaced with a floxed neo cassette via homologous recombination. (J:183989)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nlrp10 Mutation:  22 strains or lines available
References
Original:  J:173245 Elinav E, et al., NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis. Cell. 2011 May 27;145(5):745-57
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory