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Ccm2tm2.1Sbn
Targeted Allele Detail
Nomenclature
Symbol: Ccm2tm2.1Sbn
Name: cerebral cavernous malformation 2; targeted mutation 2.1, Ulrich Siebenlist
MGI ID: MGI:5085315
Synonyms: Ccm2flox
Gene: Ccm2  Location: Chr11:6546887-6596744 bp, + strand  Genetic Position: Chr11, 4.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174085
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccm2 Mutation:  31 strains or lines available
References
Original:  J:174085 Cunningham K, et al., Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations. Hum Mol Genet. 2011 Aug 15;20(16):3198-206
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory