Scrib^crn2
Chemically induced Allele Detail

Summary

• Symbol: Scrib^crn2
• Name: scribbled planar cell polarity; craniorachischisis
• MGI ID: MGI:5056373
• Gene: Scrib Location: Chr15:75919011-75941633 bp, - strand Genetic Position: Chr15, 35.29 cM
• Alliance: Scrib^crn2 page

Mutation origin

• Strain of Origin: A/J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Not Specified
• Mutation details: Identified in an ENU screen and mapped to a 4 Mb interval on chromosome 15 including Scrib. A missense mutation was identified in the 19th exon converting a highly conserved glutamic acid residue at position 800 to glycine. (J:174027)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scrib Mutation: 53 strains or lines available

References

• Original: J:174027 Stottmann RW, et al., Focusing Forward Genetics: A Tripartite ENU Screen for Neurodevelopmental Mutations in the Mouse. Genetics. 2011 Jul;188(3):615-24
• All: 1 reference(s)