About   Help   FAQ
Tg(HTT*/EGFP)190Nn
Transgene Detail
Nomenclature
Symbol: Tg(HTT*/EGFP)190Nn
Name: transgene insertion 190, Nobuyuki Nukina
MGI ID: MGI:5052377
Synonyms: HD190QG
Transgene: Tg(HTT*/EGFP)190Nn  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6 x DBA/2
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(HTT*/EGFP)190Nn expresses 1 gene
 
Mutation detailsThe human HTT promoter and exon 1, containing expanded CAG repeats, were fused to EGFP. The expanded repeat segment includes about 150 CAG repeats. This line carries 2 main fragments, one with 190 CAG repeats and one with 155 CAG repeats. (J:174269)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:174269 Kotliarova S, et al., Decreased expression of hypothalamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates. J Neurochem. 2005 May;93(3):641-53
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/17/2015
MGI 5.21
The Jackson Laboratory