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Mgat5btm1.1Cfg
Targeted Allele Detail
Nomenclature
Symbol: Mgat5btm1.1Cfg
Name: mannoside acetylglucosaminyltransferase 5, isoenzyme B; targeted mutation 1.1, Consortium for Functional Glycomics
MGI ID: MGI:5052168
Gene: Mgat5b  Location: Chr11:116918863-116986948 bp, + strand  Genetic Position: Chr11, 81.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:94077
Parent Cell Line:  CMTI-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP-flanked PGKneo cassette site was inserted upstream of exon 2 and a third loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the neo cassette. Exon 2 was subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(EIIa-cre)C5379Lmgd. (J:94077)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgat5b Mutation:  52 strains or lines available
References
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory