Rest^tm1Mlit
Targeted Allele Detail

Summary

• Symbol: Rest^tm1Mlit
• Name: RE1-silencing transcription factor; targeted mutation 1, Jian Fei
• MGI ID: MGI:5052049
• Synonyms: nrsf^flox
• Gene: Rest Location: Chr5:77413338-77434279 bp, + strand Genetic Position: Chr5, 41.61 cM
• Alliance: Rest^tm1Mlit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173834
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was flanked with a loxP site and a floxed neo cassette. (J:173834)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rest Mutation: 95 strains or lines available

References

• Original: J:173834 Cai L, et al., Ethanol-induced neurodegeneration in NRSF/REST neuronal conditional knockout mice. Neuroscience. 2011 May 5;181:196-205
• All: 7 reference(s)