About   Help   FAQ
Pinx1tm1.1Kplu
Targeted Allele Detail
Nomenclature
Symbol: Pinx1tm1.1Kplu
Name: PIN2/TERF1 interacting, telomerase inhibitor 1; targeted mutation 1.1, Kun Ping Lu
MGI ID: MGI:5013947
Gene: Pinx1  Location: Chr14:63860312-63919859 bp, + strand  Genetic Position: Chr14, 33.34 cM, cytoband C3
Varied histopathology of Pinx1tm1.1Kplu/Pinx1+ tumors

Show the 12 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171997
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Generation of the Pinx1tm1.1Kplu allele
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pinx1 Mutation:  2 strains or lines available
References
Original:  J:171997 Zhou XZ, et al., The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice. J Clin Invest. 2011 Apr 1;121(4):1266-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory