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Targeted Allele Detail
Symbol: Rfwd2tm2.1Vmd
Name: ring finger and WD repeat domain 2; targeted mutation 2.1, Vishva M Dixit
MGI ID: MGI:5013594
Synonyms: Cop1fl
Gene: Rfwd2  Location: Chr1:159232320-159347640 bp, + strand  Genetic Position: Chr1, 69.03 cM, cytoband C3
Germline Transmission:  Earliest citation of germline transmission: J:172653
Parent Cell Line:  C2 (Nagy) (ES Cell)
Strain of Origin:  C57BL/6N
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 3. A floxed neo cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neo cassette. (J:172653)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rfwd2 Mutation:  9 strains or lines available
Original:  J:172653 Vitari AC, et al., COP1 is a tumour suppressor that causes degradation of ETS transcription factors. Nature. 2011 Jun 16;474(7351):403-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory