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Ltbrtm1Mmat
Targeted Allele Detail
Nomenclature
Symbol: Ltbrtm1Mmat
Name: lymphotoxin B receptor; targeted mutation 1, Mitsuru Matsumoto
MGI ID: MGI:5013450
Gene: Ltbr  Location: Chr6:125283534-125290848 bp, - strand  Genetic Position: Chr6, 59.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:173115
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA floxed cassette containing a lacZ gene, polyadenylation sequence, FRT-flanked neo cassette, and a second polyadenylation sequence was inserted downstream of exon 1. (J:173115)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ltbr Mutation:  34 strains or lines available
References
Original:  J:173115 Mouri Y, et al., Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma. J Immunol. 2011 May 1;186(9):5047-57
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/26/2022
MGI 6.21
The Jackson Laboratory