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Stim2tm1.1Kuro
Targeted Allele Detail
Summary
Symbol: Stim2tm1.1Kuro
Name: stromal interaction molecule 2; targeted mutation 1.1, Tomohiro Kurosaki
MGI ID: MGI:5008479
Synonyms: Stim2f
Gene: Stim2  Location: Chr5:54155865-54278399 bp, + strand  Genetic Position: Chr5, 29.69 cM
Alliance: Stim2tm1.1Kuro page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172608
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 6. An additional loxP site was inserted downstream of exon 7. Cre-mediated recombination removed the neo cassette and left exons 6 and 7 floxed. (J:172608)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stim2 Mutation:  42 strains or lines available
References
Original:  J:172608 Matsumoto M, et al., The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production. Immunity. 2011 May 27;34(5):703-14
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory