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Mefvtm5.1(MEFV)Chae
Targeted Allele Detail
Nomenclature
Symbol: Mefvtm5.1(MEFV)Chae
Name: Mediterranean fever; targeted mutation 5.1, Jae Jin Chae
MGI ID: MGI:5007914
Synonyms: MefvV726A
Gene: Mefv  Location: Chr16:3707215-3718124 bp, - strand  Genetic Position: Chr16, 2.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172117
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mefv Mutation:  1 strain or line available
References
Original:  J:172117 Chae JJ, et al., Gain-of-Function Pyrin Mutations Induce NLRP3 Protein-Independent Interleukin-1beta Activation and Severe Autoinflammation in Mice. Immunity. 2011 May 27;34(5):755-68
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory