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Targeted Allele Detail
Symbol: Zdhhc9tm1Lex
Name: zinc finger, DHHC domain containing 9; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007410
Gene: Zdhhc9  Location: ChrX:47260846-47297755 bp, - strand  Genetic Position: ChrX, 25.55 cM
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThe Zdhhc9 gene consists of 10 exons. Coding exon 1 was targeted (NCBI accession NM_172465.1) by homologous recombination, whereby a genomic region of 207 bp including most of the first coding exon (exon2) was deleted. A selection cassette containing both neomycin and lacZ was also inserted. Western blot analysis of whole brain lysates confirmed the absence of full-length and any truncated protein fragment. (J:171883, J:268248)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Zdhhc9 Mutation:  6 strains or lines available
See also, data as provided by Lexicon Genetics, Inc.
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory