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Scn2btm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Scn2btm1Lex
Name: sodium channel, voltage-gated, type II, beta; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007314
Gene: Scn2b  Location: Chr9:45117876-45130070 bp, + strand  Genetic Position: Chr9, 24.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA portion of the coding region was targeted by homologous recombination. Coding exons 2 through 4 were targeted (NCBI accession XM_134787.2). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scn2b Mutation:  6 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/19/2017
MGI 6.10
The Jackson Laboratory